Scientist (Next-Gen Sequencing)

Company: Medical Science & Computing (MSC), a Dovel company
Location: Bethesda
Posted on: May 15, 2022

Job Description:

We are currently searching for a Scientist (Next-Gen Sequencing) to provide support to the National Institutes of Health (NIH). This opportunity is a full-time position with MSC and it is onsite in Bethesda, MD. Duties & Responsibilities

• Perform a wide range of complex procedures and techniques including, cell culture, molecular biology, DNA/RNA analysis, DNA/RNA isolation, DNA/RNA purification, DNA/RNA next generation (Illumina) sequencing, flow cytometry, gene cloning.
• Lead the sequencing group in developing research including planning and conducting experiments and data analysis.
• Develop protocols for use in clinical vaccine trial analyses.
• Collaborate with scientists from other organizations or institutions involved in similar or related research projects.
• lead students, post-doctoral fellows and non-doctoral research technicians on experimental design and laboratory-based methodologies.
• Maintain accurate, daily records of experiments.
• Perform high level next generation DNA/RNA sequencing data analysis.
• Manage project pipelines.
• Develop novel protocols for sequencing viral genomes by sequence alignment and primer design.
• Design and implement improved methods to existing standard next generation sequencing protocols.
• Develop protocols into SOPs for use in training material.
• Maintain and operate two workstation robots to increase library prep throughput and sample clean-up.
• Develop the technique of single cell RNA-seq.
• Train individuals from other laboratories around the world in the technique of single cell RNA-seq, as a part of program collaborations.
• Analyze sequencing data produced by different types of analyzers.
• Integrate new instruments (NovaSeq, 10x Chromium, Mosquito) to increase the project versatility of the Genome Analysis Core.
• Manage sequencing projects once they are initiated by determining costs and acceptable timelines and providing frequent updates for these collaborations.
• Knowledge of LIMS system (Clarity or LabWare) with a view to interfacing instruments.
• Work with staff to plan technical aspects of sequencing projects by suggesting innovative methods and approaches.
• Work with staff to develop and optimize assays for diverse new projects.
• Produce high quality scientific data and analysis consistently using new methods such as single cell sequencing.
• Help train post-baccalaureate IRTAs and collaborators in molecular biology assays in the core.
• Provide assistance in budget management of various projects.
• Calibrate and operate a variety of laboratory instruments under GLP guidelines and follow SOPs to perform test, analysis, and other procedures. Requirements
  • Ph.D. degree in Biology, Life Sciences or a related discipline. Three (3) years of specialized experience plus a Master's degree is equivalent to a Ph.D. Five (5) years of specialized experience plus a BA/BS degree is equivalent to a Ph.D.
  • Minimum of five (5) years of experience in biology or a related field including cell and molecular biology, immunology, and/or next generation sequencing.
  • Demonstrates experience working in a laboratory environment.
  • Demonstrates knowledge of maintaining accurate and detailed records
  • Demonstrates knowledge of proper laboratory disposal methods and safety procedures.
  • Demonstrates knowledge of budget management for various projects.
  • Demonstrates working knowledge of Good Laboratory Practices Company Description Dovel Technologies and its Family of Companies (Medical Science & Computing and Ace Info Solutions) was acquired in October 2021. Guidehouse is a leading global provider of consulting services to the public sector and commercial markets, with broad capabilities in management, technology, and risk consulting. By combining our public and private sector expertise, we help clients address their most complex challenges and navigate significant regulatory pressures focusing on transformational change, business resiliency, and technology-driven innovation. Across a range of advisory, consulting, outsourcing, and digital services, we create scalable, innovative solutions that help our clients outwit complexity and position them for future growth and success. The company has more than 12,000 professionals in over 50 locations globally. Guidehouse is a Veritas Capital portfolio company, led by seasoned professionals with proven and diverse expertise in traditional and emerging technologies, markets, and agenda-setting issues driving national and global economies. Guidehouse is an Equal Employment Opportunity / Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, national origin, ancestry, citizenship status, military status, protected veteran status, religion, creed, physical or mental disability, medical condition, marital status, sex, sexual orientation, gender, gender identity or expression, age, genetic information, or any other basis protected by law, ordinance, or regulation. Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance, including the Fair Chance Ordinance of Los Angeles and San Francisco. If you have visited our website for information about employment opportunities or to apply for a position, and you require accommodation, please contact Guidehouse Recruiting at 1- or via email at . All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation. Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse, and Guidehouse will not be obligated to pay a placement fee.

Keywords: Medical Science & Computing (MSC), a Dovel company, Bethesda , Scientist (Next-Gen Sequencing), Other , Bethesda, Maryland