Research Associate II, Single Cell and Spatial Transcriptomics with Childhood Cancer Data Initiative

Company: Frederick National Laboratory
Location: Bethesda
Posted on: March 11, 2023

Job Description:

Job Description:

Research Associate II, Single Cell and Spatial Transcriptomics with Childhood Cancer Data Initiative Job ID: req3303Employee Type: exempt full-timeDivision: Cancer Research Technology ProgramFacility: NIHLocation: NIH Campus 9000 Rockville Pike, Bethesda, MD 20892 USA The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases. Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way. PROGRAM DESCRIPTION The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community and provides dedicated support to NCI's intramural Center for Cancer Research (CCR). The dedicated units provide expertise in electron microscopy, protein characterization, mass spectrometry, protein expression, optical microscopy, and genomics. These research efforts are an integral part of CCR at the Frederick National Laboratory for Cancer Research (FNLCR), where CRTP scientists work collaboratively with intramural NCI investigators to provide research technologies and expertise.KEY ROLES/RESPONSIBILITIESWe are seeking a highly motivated Research Associate to work with the NCI Center for Cancer Research (CCR) Single Cell Analysis Facility (SCAF) to provide dedicated single cell and spatial research support for the intramural Childhood Cancer Data Initiative (CCDI). This will include close collaboration with CCDI Investigators to generate high-quality datasets for multiple projects using established single cell methods and help validate and employ emerging technologies. A major goal of this Initiative is to establish tumor cell atlases for rare pediatric malignancies.Providing state-of-the-art single cell and spatial research support to CCDI InvestigatorsPerforming single cell captures, library preparation, quality control and sequencingProcessing tissue sections for spatial transcriptomics Helping with experimental design, sample preparation and project troubleshootingWorking to implement support for advanced single cell and spatial methods more efficiently and effectively**THIS POSITION IS CONTINGENT UPON FUNDING APPROVAL** BASIC QUALIFICATIONSTo be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:Possession of a (CHEA) Bachelor's degree from an accredited college or university according to the Council for Higher Education Accreditation. (Additional qualifying experience may be substituted for the required education)Five (5) years of experience performing cell and molecular biology experimentsFamiliarity with next generation sequencing methodsAbility to obtain and maintain a security clearancePREFERRED QUALIFICATIONS Candidates with these desired skills will be given preferential consideration:Experience with NextGen library generation, DNA/RNA isolation, and DNA/RNA quantitationGeneral cell biology experience, including handling live cells and countingExperience working in a core facility or other team-based environmentDemonstrated ability to learn new technologies quicklyKnowledge and background experience in cancer biology and immunologyMust have excellent written and verbal communication skillsMust be detail-oriented, and able to manage multiple projects simultaneouslyJOB HAZARDSThis position is subject to working with or have potential for exposure to animal(s) and/or animal material(s)This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations Equal Opportunity Employer (EOE) - Minority/Female/Disabled/Veteran (M/F/D/V) - Drug Free Workplace (DFW)#readytowork

Keywords: Frederick National Laboratory, Bethesda , Research Associate II, Single Cell and Spatial Transcriptomics with Childhood Cancer Data Initiative, Other , Bethesda, Maryland