Scientist I/II, Translational Scientist

Company: Arcellx Inc
Location: Rockville
Posted on: April 1, 2026

Job Description:

Arcellx ( http://www.arcellx.com/ ) is a clinical-stage biotech company headquartered in Gaithersburg, MD and Redwood City, CA. Arcellx is focused on the development of novel cell-based cancer therapies. A team of biotechnology professionals with expertise in biologics, discovery and tumor immunology incorporate proprietary technologies into genetically engineered human immune cells therapies. Arcellx’s mission is to advance humanity by engineering cell therapies that are safer, more effective, and more broadly accessible. Primary Objective: The Scientist position is open to highly motivated candidates with a background in oncology, immunology, and translational research who are interested in working within a fast-paced biotechnology company. As a Translational Science Strategist (TSS) based in Gaithersburg, MD, you will join a dynamic Translational Sciences team responsible for developing, implementing, and supporting translational strategy as projects move from discovery to early clinical development. The TSS will be an integral member of cross-functional project teams and will be accountable for developing and driving implementation of translational plans, identifying preclinical models with mechanistic alignment to human disease, defining the preclinical and early clinical biomarker strategy, and helping to build the early clinical development plan. Main Accountabilities: Contribute relevant scientific expertise, strategy, and experimentally-derived insights as a member of multidisciplinary project teams working to drive the preclinical to clinical translation of pipeline assets Plan, design, and execute IND-enabling pharmacology, pharmacokinetic and toxicology studies by applying knowledge of disease-associated pathways, preclinical models, and drug development Contribute to the preparation of IND applications and other regulatory documents, as appropriate Collaborate cross-functionally to enable translation of preclinical hypotheses into clinical biomarker strategies and to guide patient stratification Design and conduct studies to inform disease area strategy for target selection and validation Establish and cultivate relationships with external CRO collaborators for basic and translational research Analyze and interpret experimental data readouts and present results at internal meetings and scientific conferences Maintain an awareness of new/emerging techniques, tools and clinical findings relevant to the field Preferred Qualifications: PhD, MD or MD/PhD degree in a relevant scientific field ( e.g. , cancer biology, immunology, molecular biology, bioinformatics) with 0-2 years experience in drug discovery or drug development Demonstrated record of research accomplishment as evidenced by publications or major contributions to drug development milestones Experience with large, multimodal data sets and familiarity with techniques for exploring associations of biomarkers with clinical outcomes Strategic thinker with proven leadership skills and/or prior project team leadership roles Proficiency in distilling complex issues and clearly articulating viable paths forward Competencies: Commitment to ethical scientific investigations and rigorous experimental methods Ability and desire to multitask and function in a fast-paced entrepreneurial environment Sense of urgency in performance of duties Interpersonal skills that promote a collaborative and productive team environment Outstanding presentation and communication skills

Keywords: Arcellx Inc, Bethesda , Scientist I/II, Translational Scientist, Science, Research & Development , Rockville, Maryland